HYPOTENSIVE ACTION OF N-ETHOXYCARBONYL-3-MORPHOLINOSYDNONIMINE, SIN-10
نویسندگان
چکیده
منابع مشابه
Metabolic fate of 5-ethoxycarbonyl-3-morpholinosydnonimine (SIN-10). 1. Absorption, excretion and tissue distribution in rats and mice.
chemical structure. The pharmacological studies on SIN-10 by Takenaka et al. (2) showed a sustained hypotensive effect in rabbits. The similar effect was also confirmed in the dog, cat and rat by Kikuchi et al. (3). In order to provide a biochemical basis for the pharmacological and toxicological mechanisms, the metabolic aspects of SIN-10 have been studied in rats and mice. The present paper d...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1970
ISSN: 0021-5198
DOI: 10.1254/jjp.20.102